Primary hyperaldosteronism presenting as resistant hypertension

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Idiopathic Hyperaldosteronism Presenting as Resistant Hypertension

PrimaryAaldosteronism (PA) is a group of endocrine disorders in which aldosterone production is inappropriately high, autonomous of the renin-angiotensin system and not suppressed by sodium loading1. Bilateral idiopathic hyperaldosteronism (IHA) and aldosterone producing adenoma (APA) are the most common subtypes of PA. It is estimated that more than 10% of patients with secondary hypertension ...

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Normokalemic hyperaldosteronism in patients with resistant hypertension.

BACKGROUND Primary aldosteronism is a common cause of non-renal secondary hypertension. A correct diagnosis results in curing the hypertension or targeting appropriate pharmacotherapy. In patients with low renin resistant hypertension (after treatment with three or more different anti-hypertensive drugs the blood pressure remains above 140/90 mmHg), screening for aldosteronism is mandatory. O...

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Clarification of hypertension – Diagnosis of primary hyperaldosteronism

Primary hyperaldosteronism (PH) is the most common cause of secondary hypertension. Apart from hypertension, hypokalaemia was hitherto considered to be the classical cardinal symptom. Its presence was therefore also usually a prerequisite for further diagnostic clarification in respect of PH. However, numerous new studies in normokalaemic hypertension patients now show that serum potassium leve...

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Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.

BACKGROUND Results of several studies published since 1999 suggest that primary hyperaldosteronism (also known as Conn's syndrome) affects more than 10% of people with hypertension; however, such a high prevalence has also been disputed. Experts generally agree that resistant hypertension has the highest prevalence of primary hyperaldosteronism, on the basis of small studies. We aimed to assess...

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Hyperaldosteronism among black and white subjects with resistant hypertension.

Recent reports suggesting that the prevalence of primary hyperaldosteronism may be higher than historically thought have relied on an elevated plasma aldosterone concentration/plasma renin activity ratio to either diagnose or identify subjects at high risk of having primary hyperaldosteronism and have not included suppression testing of all evaluated subjects. In this prospective study of 88 co...

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ژورنال

عنوان ژورنال: Medicine: Case Reports and Study Protocols

سال: 2021

ISSN: 2691-3895

DOI: 10.1097/md9.0000000000000087